The Matriskin Story

Your skin will remember…

Born in France at the meeting point of medicine and nature, Matriskin exists to reawaken the skin to its healthiest blueprint through biotechnology and biomimicry.

Matriskin is more than skincare. It is the awakening of what your skin already knows. — Matriskin Biotechnology

Origins: where medicine meets nature

In the early 2000s, leading aesthetic surgeons noticed a simple truth: surgical excellence alone was not enough. When skin lacked vitality—its collagen network weakened, its elasticity reduced—outcomes suffered. Patients needed preparation; their skin needed to remember how to regenerate.

This observation sparked a new philosophy: instead of forcing change from the outside, inspire the skin to recover its own codes for health from within.

Founder: Dr Pierre Huet

French allergist and researcher trained at the University of Paris; member of the Société Française de Médecine Esthétique.

Dr Pierre Huet founded ESPA SA, a French biotechnology laboratory at the forefront of dermal science. From this work, Matriskin Biotechnology emerged—designed as a clinical-grade system originally reserved for dermatologists and plastic surgeons.

Our approach: biotechnology & biomimicry

Rather than relying on superficial correction, Matriskin mirrors the skin’s natural systems—stimulating cellular communication, reactivating hydration channels, and restoring biological architecture from within. This biomimetic approach is our signature: science inspired by life itself.

Cellular communication

Support signalling so skin “remembers” how to renew.

Hydration channels

Reactivate water pathways for resilient, elastic tissue.

Structural integrity

Reinforce collagen-elastic networks for firmer tone and texture.

Barrier intelligence

Calm reactivity and protect the skin’s living ecology.

A quiet revolution in aesthetic medicine

For over two decades, Matriskin remained a professional secret—trusted in operating rooms and clinics where performance is non-negotiable. The philosophy remained constant: empower the skin to do what it was designed to do.

  • Early 2000sClinical formulations developed for pre- and post-procedure care.
  • 2000s–2010sGrowth through specialist dermatology and plastic-surgery channels.
  • 2020With clinic access limited worldwide, access expands from doctors-only to at-home care.

Today: clinical precision, at home

Still crafted in small batches in France and driven by ESPA’s original mission, Matriskin bridges clinical precision with the living intelligence of the skin. Each formulation is designed to activate the skin’s own regenerative codes—reviving tone, texture, and resilience through nature’s blueprint.

Your skin will remember. The original promise of Matriskin
Matriskin Biotechnology
Biotechnology-driven, biomimetic skincare born in France.